Spruce Biosciences Inc (SPRB)

Currency in USD
69.3200
+1.5200(+2.24%)
Closed·
67.5000-1.8200(-2.63%)
·
SPRB is not included in our AI-picked strategies. See which stocks are.
Fair Value
Day's Range
66.820071.4600
52 wk Range
4.2750240.0000
Key Statistics
Prev. Close
67.8
Open
68.01
Day's Range
66.82-71.46
52 wk Range
4.275-240
Volume
54.64K
Average Vol. (3m)
45.65K
1-Year Change
651.4363%
Book Value / Share
39.72
Fair Value
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Fair Value Upside
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SPRB Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
198.2500
Upside
+185.99%
Members' Sentiments
Bearish
Bullish
ProTips
Suffers from weak gross profit margins

Spruce Biosciences Inc News & Analysis

Show more

Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Strong Buy

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.

Spruce Biosciences Inc SWOT Analysis


Strategic Horizons
Learn about Spruce's expansion into MDD and PCOS treatments, diversifying beyond CAH and potentially reshaping the company's market position and valuation
Financial Health
Discover Spruce's $70M cash position, runway through 2025, and efficient cash management, balanced against rapid cash burn and market cap challenges
Market Dynamics
Delve into the competitive landscape of CAH treatment, with Spruce Biosciences vying against Neurocrine's crinecerfont in a market of 20,000-30,000 U.S. patients
Tildacerfont Trials
Explore the pivotal CAHmelia-204 and CAHptain-205 trials, testing tildacerfont's efficacy in reducing glucocorticoid doses while maintaining androgen control in CAH patients
Read full SWOT analysis

Compare SPRB to Peers and Sector

Metrics to compare
SPRB
Peers
Sector
Relationship
P/E Ratio
−2.4x−3.4x−0.5x
PEG Ratio
−0.05−0.090.00
Price / Book
2.2x15.1x2.6x
Price / LTM Sales
-20.9x3.2x
Upside (Analyst Target)
172.9%56.8%45.7%
Fair Value Upside
Unlock2.7%4.8%Unlock

Analyst Ratings

4 Buy
0 Hold
0 Sell
Ratings:
4 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 198.2500
(+185.99% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Citizens
Buy170.00+145.24%-MaintainMar 25, 2026
H.C. Wainwright
Buy200.00+188.52%220.00MaintainFeb 19, 2026
Citizens
Buy180.00+159.67%259.00MaintainFeb 18, 2026
Oppenheimer
Buy283.00+308.25%-New CoverageDec 23, 2025
H.C. Wainwright
Buy220.00+217.37%-New CoverageDec 22, 2025

Earnings

Latest Release
Mar 09, 2026
EPS / Forecast
-11.29 / -0.15
Revenue / Forecast
-- / 250K
EPS Revisions
Last 90 days

SPRB Income Statement

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FAQ

What Is the Spruce (SPRB) Stock Price Today?

The Spruce stock price today is 69.3200 USD.

What Stock Exchange Does Spruce Trade On?

Spruce is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Spruce?

The stock symbol for Spruce is "SPRB."

What Is the Spruce Market Cap?

As of today, Spruce market cap is 93.0400M USD.

What Is Spruce's Earnings Per Share (TTM)?

The Spruce EPS (TTM) is -50.8298.

When Is the Next Spruce Earnings Date?

Spruce will release its next earnings report on Nov 17, 2025.

From a Technical Analysis Perspective, Is SPRB a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Buy.

How Many Times Has Spruce Stock Split?

Spruce has split 1 times.

How Many Employees Does Spruce Have?

Spruce has 8 employees.

What is the current trading status of Spruce (SPRB)?

As of Apr 16, 2026, Spruce (SPRB) is trading at a price of 69.3200 USD, with a previous close of 67.8000 USD. The stock has fluctuated within a day range of 66.8200 USD to 71.4600 USD, while its 52-week range spans from 4.2750 USD to 240.0000 USD.

What Is Spruce (SPRB) Price Target According to Analysts?

The average 12-month price target for Spruce is 198.2500 USD, with a high estimate of 283 USD and a low estimate of 140 USD. 4 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Strong Buy. The stock has an +185.99% Upside potential.

What Is the SPRB After Hours Price?

SPRB's last after hours stock price is 67.5000 USD, the stock has decreased by -1.8200, or -2.6300%.
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